Steroids Decrease Prevalence of Positive Tuberculin Skin Test in Rheumatoid Arthritis: Implications on Anti-TNF Therapies
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چکیده
منابع مشابه
Steroids Decrease Prevalence of Positive Tuberculin Skin Test in Rheumatoid Arthritis: Implications on Anti-TNF Therapies
Tuberculin skin test has been used as an indicator of latent tuberculosis in patients with Rheumatoid Arthritis (RA) before administration of biologicals. Effect of Disease modifying antirheumatic drugs (DMARDs) and steroids on the result of tuberculin skin test (TST) may have important implications in interpretation of results of this test. Objectives. To find the prevalence of positive TST in...
متن کاملKey words: rheumatoid arthritis, treatment, disease-modifying anti-rheumatic drugs, anti-TNF agents, new therapies
1Rheumatology Unit, Department of Experimental and Clinical Medicine, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Italy; 2Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy; 3Department of Rheumatology, University of Perugia, Italy; 4Department of Rheumatology, Policlinico Le Scotte, University of Siena, Italy. Andrea Calabrò, M...
متن کاملPrevalence and predictors of positive tuberculin skin test results in a research laboratory.
Latent tuberculosis was studied in a research laboratory. A prevalence of positive tuberculin skin test results (>or= 15 mm) of 20% was found and the main predictors were place of birth in a foreign country with high prevalence of tuberculosis and a history of contact with patients with untreated active tuberculosis.
متن کاملEtanercept therapy in patients with a positive tuberculin skin test.
INTRODUCTION Etanercept (Enbrel), a tumor necrosis factor-alpha (TNF-alpha) antagonist, is commonly used for the treatment of a variety of rheumatic diseases. Tuberculosis (TB) infections have been associated with chronic TNF-alpha blocking therapy, and there is concern that such therapy may predispose patients to TB reactivation. In this study, we attempted to evaluate the frequency of latent ...
متن کاملBiological Therapies for Rheumatoid Arthritis: Non-TNF Inhibitors
directed at interrupting the inflammatory process, which, if left unchecked, causes irreversible joint damage, deformity and long-term functional impairment. The earlier therapy is initiated, the better the long-term outcomes in patients with RA. Methotrexate is the main disease-modifying anti-rheumatic drug (DMARD) used for the treatment of RA and remains the gold standard of first-line therap...
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ژورنال
عنوان ژورنال: Interdisciplinary Perspectives on Infectious Diseases
سال: 2014
ISSN: 1687-708X,1687-7098
DOI: 10.1155/2014/430134